姓名 仇梁林
职称 副教授
个人简介：
医学博士，营养与食品卫生学系教师、副教授、硕士研究生导师，中国营养学会会员、江苏省毒理学会青年委员会常务委员。本科毕业于南通医学院临床医学系；硕士毕业于英国365公司；博士毕业于南京医科大学英国365公司；曾在英国Leicester University短期交流并在美国University of Maryland从事过两年的博士后研究工作。近年来主持完成多项国家、省市级科研项目，在国际权威期刊Environmental Health Perspectives、Environmental Science & Technology、Free Radical Biology and Medicine等杂志上发表学术论文十余篇。
招生方向：
营养与食品卫生学
代表论文：
[1] Jinchen Jiang, Haixia Meng, Zhenhao Shu, Nannan Zhao, Xiaojun Lin, Jianglan Li, Mingjun Qin, Siyu Wu, Lianglin Qiu. 6:2 Chlorinated polyfluoroalkyl ether sulfonate (6:2 Cl-PFAES), a PFOS alternative, impairs testosterone synthesis in Leydig cells by targeting lipophagy via the SIRT1-FOXO1-RAB7 axis: an in vitro and in vivo study. Environmental Science & Technology. 2026 Jan 28. doi: 10.1021/acs.est.5c11476. (中科院一区，Nature Index, IF：11.30)
[2] Shaokai Zheng, Nannan Zhao, Xiaojun Lin, Lianlian Jiang, Chong Qiu, Jinchen Jiang, Zhenhao Shu, Yingyun Qian, Bo Liang, Lianglin Qiu. Fine particulate matter (PM2.5) and the blood-testis-barrier: an in vivo and in vitro mechanistic study. EnvironmentalHealth Perspectives. 2025 Apr;133(3-4):47006 (中科院一区，Nature Index, IF：9.80)
[3] Shaokai Zheng, Jiang Jinchen, Shu Zhenhao, Qiu Chon, Jiang Lianlian, Zhao Nannan, Lin Xiaojun, Qian Yinyun, Liang Bo, Qiu Lianglin. Fine particulate matter (PM2.5) induces testosterone disruption by triggering ferroptosis through SIRT1/HIF-1α signalingpathway in male mice. Free Radical Biology and Medicine. 2024 Aug 20; 221:40-51(中科院二区，IF：7.48)
[4] Jiang Lianlian, Lin Xiaojun, Jiang Jinchen, Qiu Chon, Zheng Shaokai, Zhao Nannan, Shu Zhenhao, Qian Yinyun, Qiu Lianglin. METTL3-m6A-SIRT1 axis affects autophagic flux contributing to PM2.5-induced inhibition of testosterone production in Leydig cells.Science of the Total Environment. 2024 Mar 25; 918:170701. (中科院一区，IF：9.86)
[5] Jiang Jinchen, Shu Zhenhao, Qiu Lianglin. Adverse effects and potential mechanisms of polystyrene microplastics (PS-MPs) on the blood-testis barrier. Environmental Geochemistry and Health. 2024 Jun 7; 46(7): 238 (中科院三区，IF：4.26)
[6] Li Ting, Jiang Lianian, Zheng Shaokai, Qiu Chon, Zhao Nannan, Lin Xiaojun, Ren Hang, Huang Jiyan, Wang Hongxia, Qiu Lianglin. Organic anion transporting polypeptide 3a1 is a novel influx pump for Perfluorooctane sulfonate in Sertoli cells and contributes to its reproductive toxicity. Chemosphere. 2023 Dec: 345:140428. (中科院二区，IF：8.81)
[7] Shaokai Zheng, Ting Li, Lianglin Qiu. Identification of Potential Crucial Genes in Testicular Germ Cell Tumors: A Bioinformatical Integrated Analysis. Cancer Biomarkers. 2023. Cancer Biomark. 2023;38 (2):261-272. (中科院三区，IF：3.18)
[8] Shaokai Zheng, Nannan Zhao, Xiaojun Lin, Lianglin Qiu. Impacts and potential mechanisms of fine particulate matter (PM2.5) on male testosterone biosynthesis disruption. Reviews on Environmental Health. 2023 Sep 1;39(4):777-789 (中科院四区，IF：3.97)
[9] ShaokaiZheng, Lianlian Jiang, Lianglin Qiu. The effects of fine particulate matter on the blood-testis barrier and its potential mechanisms. Reviews on Environmental Health. 2022 Nov 29;39(2):233-249. (中科院四区，IF：3.97)
[10] Huang Jiyan, Ren Hang, Chen Anni, Li Ting, Wang Hongxia, Jiang Lianlian, Zheng Shaokai, Qi Han, Ji Binyan, Wang Xipei, Qu Jianhua, Zhao Jianya, Qiu Lianglin. Perfluorooctane sulfonate induces suppression of testosterone biosynthesis via Sertoli cell-derived exosomal/miR-9-3p downregulating StAR expression in Leydig cells. Environmental Pollution. 2022 May 15:301:118960. (中科院二区，IF：8.07)
[11] Qiu Lianglin, Chen Minjie, Wang Xiaoke, Chen Sufang, Ying Zhekang. PM2.5 Exposure of Mice during Spermatogenesis: A Role of Inhibitor κB Kinase 2 in Pro-Opiomelanocortin Neurons. Environmental Health Perspectives. 2021 Sep;129(9):97006. (中科院一区，Nature Index, IF：11.35)
[12] Qiu Lianglin, Wang Hongxia, Dong Tianyi, Huang Jiyan, Li Ting, Ren Hang, Wang Xipei, Qu Jianhua, Wang Shoulin. Perfluorooctane sulfonate (PFOS) disrupts testosterone biosynthesis via CREB/CRTC2/StAR signaling pathway in Leydig cells. Toxicology. 2021 Feb 15:449:152663. (中科院二区，IF：4.22)
[13] Chen Minjie, Xu Yanyi, Wang Wanjun, Wang Xiaoke, Qiu Lianglin, Chen Sufang, Kan Haidong, Ying Zhekang. Paternal Exposure to PM2.5 Programs Offspring's Energy Homeostasis. Environmental Science & Technology. 2021 May 4;55(9):6097-6106. (中科院一区，Nature Index, IF：9.03)
[14] Chen Sufang, Chen Minjie, Wei Wei, Qiu Lianglin, Zhang Li, Cao Qi, Ying Zhekang. Glucose Homeostasis following Diesel Exhaust Particulate Matter Exposure in a Lung Epithelial Cell-Specific IKK2-Deficient Mouse Model. Environmental Health Perspectives.2019. May;127(5):57009. (中科院一区，Nature Index, IF：11.35)
[15] Qiu Lianglin, Wang Chao, Yao Shen, Li Na, Hu Yuhuan, Yu Yongquan, Xia Rong, Zhu Jiansheng, Ji Minghui, Zhang Zhan, Wang Shoulin. Fenvalerate induces oxidative hepatic lesions through an overload of intracellular calcium triggered by the ERK/IKK/NF-κB pathway. The FASEB Journal. 2019 Feb;33(2):2782-2795. (中科院二区，IF：5.19)
[16] Qiu Lianglin, Chen Minjie, Wang Xiaoke, Qin Xiaobo, Chen Sufang, Qian Yingyun, Liu Zhenzhen, Cao Qi, Ying Zhekang. Exposure to Concentrated Ambient PM2.5 Compromises Spermatogenesis in a Mouse Model: Role of Suppression of Hypothalamus-Pituitary-Gonads Axis. Toxicological Sciences. 2018 Mar 1;162(1):318-326. (中科院二区，IF：4.85)
[17] Chen Minjie, Qin Xiaobo, Qiu Lianglin, Chen Sufang, Zhou Huifen, Xu Yanyi, Hu Ziying, Zhang Yuhao, Cao Qi, Ying Zhekang. Concentrated Ambient PM2.5-Induced Inflammation and Endothelial Dysfunction in a Murine Model of Neural IKK2 Deficiency. Environmental Health Perspectives. 2018 Feb 5;126(2):027003. (中科院一区，Nature Index, IF：9.03)
[18] Chen Minjie, Liang Shuai, Qin Xiaobo, Zhang Li, Qiu Lianglin, Chen Sufang, Hu Ziying, Xu Yanyi, Wang Wanjun, Zhang Yuhao, Cao Qi, Ying Zhekang. Prenatal exposure to diesel exhaust PM (2.5) causes offspring β cell dysfunction in adulthood. American Journal of Physiology Endocrinology & Metabolism. 2018 Jul 1;315(1): E72-E80. (中科院二区，IF：4.31)
[19] Chen Sufang, Wei Wei, Chen Minjie, Qin Xiaobo, Qiu Lianglin, Zhang Li, Zhang Yuhao, Cao Qi, Ying Zhekang. TNF Signaling Impacts Glucagon-Like Peptide-1 Expression and Secretion. Journal of Molecular Endocrinology. 2018 Oct 15;61(4):153-161. (中科院二区，IF：5.09)
[20] Wang Xiaoke, Chen Minjie, Zhong Mianhua, Hu Ziying, Qiu Lianglin, Rajagopalan Sanjay, Fossett Nancy G, Chen Lungchi, Ying Zhekang. Exposure to Concentrated Ambient PM2.5 Shortens Lifespan and Induces Inflammation-Associated Signaling and Oxidative Stress in Drosophila. Toxicological Sciences. 2017 Mar 1;156(1):199-207. (中科院二区，IF：4.85)
[21] Qiu Lianglin, Qian Yingyun, Liu Zhenzhen, Wang Chao, Qu Jianhua, Wang Xiaoke, Wang Shoulin. Perfluorooctane sulfonate (PFOS) disrupts blood-testis barrier by down-regulating junction proteins via p38 MAPK/ATF2/MMP9 signaling pathway. Toxicology. 2016 Dec 12; 373:1-12. (中科院二区，IF：4.22)
[22] Qu Jianhua, Lu Chuncheng, Xu Cheng, Chen Gang, Qiu Lianglin, Jiang Junkang, Ben Shuai, Wang Yubang, Gu Aihua, Wang Xinru. Perfluorooctane sulfonate-induced testicular toxicity and differential testicular expression of estrogen receptor in male mice. Environmental Toxicology and Pharmacology. 2016 Jul; 45:150-157. (中科院三区，IF：4.86)
[23] Qiu Lianglin, Zhang Xuhui, Zhang Xiaoming, Zhang Yudong, Gu Jun, Chen Minjian, Zhang Zhan, Wang Xinru, Wang Shoulin. Sertoli cell is a potential target for perfluorooctane sulfonate-induced reproductive dysfunction in male mice. Toxicological Sciences. 2013 Sep;135(1):229-240. (中科院二区，IF：4.84)
[24] Qiu Lianglin, Wang Xuan, Zhang Xuhui, Zhang Zhan, Gu Jun, Liu Lu, Wang Yubang, Wang Xinru, Wang Shoulin. Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A. Toxicological Letter. 2013 May 23;219(2):116. (中科院.二区，IF：4.37)
[25] Lu HY, Qiu LL, Yang XJ, Zhang XM, Zhang Z, Wang SL. Optimization of heme precursors for the expression of human cytochrome P450 2A13 and its co-expression with oxidoreductase in baculovirus/sf9 system. 2013. J Biochem 153(6):555-63 (中科院三区，IF：3.30)
科研项目：（近五年的）
1.主持完成国家自然科学基金青年项目一项（81302452）
2.主持完成江苏省科技厅自然科学基金面上项目一项（BK20221374）
3.主持完成江苏省教育厅高等学校自然科学研究项目一项（12kJB330004）
4.主持完成江苏省教育厅高等学校自然科学研究项目一项（18kJB330004）
5.主持完成南通市科技局基础研究项目一项（JC2019021）
6.主持完成365英国上市集团博士科研人员启动基金项目一项。
获得奖项：（近五年的）
1）365英国上市集团优秀教育工作者
2) 江苏省预防医学会三等奖
3) 南通市第十届科技论文奖
